Cherry Angiomas Explained: Symptoms, Treatments, and Lifestyle Tips

By BINDHULATHA HARIKUMAR -
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  Cherry Angiomas Explained: Symptoms, Treatments, and Lifestyle Tips Cherry angiomas are small, benign skin growths that are typically bright red, due to the collection of blood vessels inside them. While they are harmless, their appearance can be concerning or undesirable for some individuals. In this comprehensive guide, we will delve into the symptoms, causes, treatment options, natural remedies, and lifestyle tips to manage cherry angiomas effectively. What Is Cherry Angiomas? Cherry angiomas, also known as senile angiomas or Campbell de Morgan spots, are non-cancerous lesions that appear on the skin. They are common among adults, especially those over the age of 30. These spots can vary in size, ranging from a pinpoint to a quarter-inch in diameter. Most cherry angiomas are circular or oval and have a smooth, dome-shaped surface. While the exact cause of cherry angiomas is unknown, they are believed to be linked to genetic factors, aging, hormonal changes, and certain...
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PHYSIOLOGY OF WOUND HEALING : SHORT

By BINDHULATHA HARIKUMAR -

 

PHYSIOLOGY OF WOUND HEALING


When your skin is injured, a complex process called wound healing begins. It involves different cells, tissues, and biochemical signals working together to repair the damaged area.

INFLAMMATORY PHASE

The first stage is called the inflammatory phase, which begins immediately after the injury and can last up to a week. This phase is characterized by the release of chemicals that cause blood vessels to dilate and white blood cells to move into the wound. The white blood cells help to remove any bacteria or debris from the injury site.

PROLIFERATIVE PHASE

The second stage is called the proliferative phase, which can last up to three weeks. During this phase, the body produces new blood vessels to supply the wound with oxygen and nutrients. Fibroblasts, which are cells that produce collagen, are also activated to help rebuild the damaged tissue. The wound begins to close, and new tissue starts to grow.

MATURATION OR REMODELLING PHASE

The final stage is called the maturation or remodeling phase, which can last for up to two years. During this phase, the new tissue becomes stronger and more flexible, and the wound becomes less noticeable. The collagen fibers reorganize, and the scar tissue matures.

Overall, wound healing is a complex process that involves many different steps and cell types. It is important to keep the wound clean and protected to promote proper healing. If you have a wound that is not healing properly, it is important to seek medical attention.

Flow chart on the physiology of wound healing:

A Comprehensive Review of Advanced Biopolymeric Wound Healing Systems - ScienceDirect

 

 

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1.     Wound occurrence

2.     Hemostasis (blood clotting)

3.     Inflammatory phase

·        Release of inflammatory mediators (histamine, cytokines, and chemokines)

·        Migration of immune cells (neutrophils and macrophages)

·        Removal of debris and bacteria

4.     Proliferative phase

·        Granulation tissue formation

·        Angiogenesis (formation of new blood vessels)

·        Epithelialization (formation of new skin)

·        Formation of extracellular matrix (ECM)

·        Fibroblast proliferation and collagen synthesis

5.     Remodeling phase

·        Collagen remodeling and cross-linking

·        Scar formation

·        Increased tensile strength of the wound.

6.     Wound closure

Explanation of the flow chart:

The physiology of wound healing is a complex process that involves various stages, starting from the occurrence of the wound to its closure. The first stage in wound healing is hemostasis, which is the process of blood clotting to stop bleeding. Once the bleeding stops, the inflammatory phase begins.

During the inflammatory phase, various inflammatory mediators such as histamine, cytokines, and chemokines are released, leading to the migration of immune cells such as neutrophils and macrophages to the site of injury. These immune cells remove debris and bacteria, preparing the wound for the next phase.

The proliferative phase is characterized by the formation of granulation tissue, angiogenesis, epithelialization, and the formation of extracellular matrix (ECM). Fibroblasts proliferate and synthesize collagen, which provides the tensile strength required for wound closure.

The final stage of wound healing is the remodeling phase, where the newly synthesized collagen undergoes remodeling and cross-linking, leading to the formation of a scar. The scar tissue has increased tensile strength, which is necessary for wound closure and tissue repair.

CONCLUSION

In conclusion, wound healing is a complex process that involves various stages, including hemostasis, inflammation, proliferation, and remodeling, leading to wound closure and tissue repair.

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